Regulation of Nitrite Reductase

Nitrite Reductase in Rice Seedlings

1. In rice seedlings synthesis of methyl viologen-nitrite reductase was stimulated by light, as was that of NADH-nitrate oxidoreductase (EC 1.6.6.1). A small residual effect of light on the synthesis of the enzymes persisted in the dark for a short time. 2. In etiolated seedlings exposed to light and nitrate, a lag period of 3 h was necessary before enzyme synthesis commenced, whereas in green ...

Activation of Nitrite Reductase from Escherichia coli

Nitrite reductase from Escherichia coli K12 requires the presence of NAD+, one of the products of the reduction ofNO2by NADH, for full activity. The effect is observed with both crude extracts and purified enzyme. NAD+ also acts as a product inhibitor at high concentrations, and plots of initial rate against NAD+ concentration are bell-shaped. The maximum occurs at about 1 mM-NAD+, but increase...

Boletus edulis Nitrite Reductase Reduces Nitrite Content of Pickles and Mitigates Intoxication in Nitrite-intoxicated Mice

Pickles are popular in China and exhibits health-promoting effects. However, nitrite produced during fermentation adversely affects health due to formation of methemoglobin and conversion to carcinogenic nitrosamine. Fruiting bodies of the mushroom Boletus edulis were capable of inhibiting nitrite production during pickle fermentation. A 90-kDa nitrite reductase (NiR), demonstrating peptide seq...

0099. Nitrite reductase activity during sepsis

Introduction Nitric oxide (NO) excess is considered to be the main cause of hypotension in sepsis. Research has mainly focussed upon NO production by isoforms of NO synthase (NOS). However, alternative pathways may make an important contribution, including nitrite (NO2 ) reduction by the reductase activity possessed by numerous hemeand pterin-based enzymes. The temporal contribution of these pa...

A Copper Nitrosyl in Nitrite Reductase